Timely referral to urology is essential to ensure early diagnosis and treatment.

Consider referral when:

• PSA levels exceed age-specific thresholds or show rapid rises over time.
• Abnormal digital rectal examination (DRE) findings - where applicable
• Patient preference after shared decision-making regarding further investigation.

Key points

• Early referral can improve prognosis and expand treatment options.
• Document rationale for referral clearly in patient records.
• Maintain communication with urology teams to track outcomes and follow-up.

The UK NSC’s draft recommendation is to:

• offer a targeted national prostate cancer screening programme to men with confirmed BRCA1 or BRCA2 gene variants every 2 years, from age 45 to age 61
• not recommend population screening
• not recommend targeted screening of Black men
• not recommend targeted screening of men with family history